HPLC Column, RP Cyano, Wide Pore, 5um, 4.6mm ID x 50mm Length, 300A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Cyano™ Wide Pore HPLC Columns are designed for reversed-phase separations of larger polar and neutral compounds where alternative selectivity to traditional alkyl-bonded phases is desired. Manufactured using ultra-high purity silica bonded with a three-carbon ligand and terminal Cyano functionality, this stationary phase provides unique chromatographic characteristics that make it an excellent choice for USP L10 methods involving larger molecules. The 300Å wide pore structure improves analyte accessibility while maintaining the distinct selectivity of Cyano chemistry.
68534-05P-3M is packed with 5 µm RP Cyano™ Wide Pore particles in a 4.6 mm ID x 50 mm format with a 300Å pore size. The 5 µm particle size provides lower operating backpressure than smaller particles while maintaining excellent efficiency and reproducibility. The short 50 mm column length is ideal for rapid analyses, high-throughput workflows, and method development applications where fast run times are important.
The RP Cyano™ Wide Pore stationary phase is not end capped and is frequently used for proteins, peptides, enzymes, natural products, and other larger polar or neutral compounds in reversed-phase HPLC. Compared to non-modified silica columns, it provides shorter retention times and faster equilibration between runs. Packed and shipped in reversed-phase solvents. See Cogent NP Cyano Columns Packed in Normal-Phase Solvents for applications requiring normal-phase chromatography.
Key Benefits
RP Cyano™ Wide Pore stationary phase
USP L10 equivalent chemistry
Ultra-high purity silica support
Three-carbon linker with terminal Cyano group
Not end capped
300Å pore size
Suitable for reversed-phase chromatography
Enhanced accessibility for larger molecules
Faster equilibration between runs
Alternative selectivity to C18 and C8 columns
Typical Applications
Reversed-phase HPLC
USP L10 methods
Protein analysis
Peptide separations
Enzyme analysis
Natural product analysis
Polar compound separations
Neutral compound separations
Method development
High-throughput laboratories
Specifications
Product Type: HPLC Column
Stationary Phase: RP Cyano™ Wide Pore
Chromatography Mode: Reversed Phase
USP Classification: L10
Particle Size: 5 µm
Pore Size: 300Å
Column Dimensions: 4.6 mm ID x 50 mm
Recommended Flow Rate: 1.0–2.0 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L10 equivalent chemistry
Not end capped
Designed for larger molecules including proteins, peptides, and enzymes
Wide pore structure improves accessibility for large analytes
Provides alternative selectivity compared to C18 and C8 columns
Faster equilibration than non-modified silica columns
Short 50 mm length helps reduce run times and solvent consumption
Packed and shipped in reversed-phase solvents