Catalog Number - 68524-15P-3M

Cogent RP Phenyl™ Wide Pore HPLC Columns are designed for reversed-phase separations involving larger molecules that benefit from aromatic selectivity and enhanced pore accessibility. Manufactured using ultra-high purity silica bonded with a three-carbon linker and terminal phenyl functionality, this stationary phase is fully double end-capped to minimize secondary interactions and provide highly reproducible chromatographic performance. The 300 Å wide pore structure improves analyte access to the stationary phase, making this column an excellent alternative for USP L11 methods involving larger compounds and for new method development.

68524-15P-3M is packed with 5 µm RP Phenyl™ Wide Pore particles featuring a 300 Å pore size in a 4.6 mm ID x 150 mm format. The wide pore structure improves mass transfer for larger molecules, including peptides and complex natural products, while the 5 µm particle size provides excellent chromatographic performance with moderate operating pressures. The 150 mm column length delivers increased resolution and peak capacity, making it ideal for complex separations requiring enhanced chromatographic performance.

The 4.6 mm ID x 150 mm format is well suited for reversed-phase separations of large positional isomers, peptides, natural products, and related compounds. Typical flow rates are approximately 0.8-1.5 mL/min depending on mobile phase composition and application requirements.

Key Benefits

• RP Phenyl™ Wide Pore stationary phase

• USP L11 equivalent chemistry

• Ultra-high purity silica support

• Fully double end-capped

• Phenyl bonded phase

• 300 Å pore size

• Suitable for reversed-phase HPLC

• Enhanced aromatic selectivity

• Improved accessibility for larger molecules

• Increased resolution and peak capacity

Typical Applications

• Large positional isomer separations

• Peptide analysis

• Natural product analysis

• Biomolecule separations

• Pharmaceutical method development

• Reversed-phase HPLC

• Large molecule analysis

• Aromatic compound separations

• Research and development

• Method optimization

Specifications

• Product Type: HPLC Column

• Stationary Phase: RP Phenyl™ Wide Pore

• Chromatography Mode: Reversed Phase

• USP Classification: L11

• Particle Size: 5 µm

• Pore Size: 300 Å

• Column Dimensions: 4.6 mm ID x 150 mm

• Recommended Flow Rate: 0.8-1.5 mL/min

• Column Hardware: Stainless Steel

• Brand: Cogent

Important Notes

• Suitable for reversed-phase chromatography

• USP L11 equivalent chemistry

• Fully double end-capped stationary phase

• Wide pore design improves accessibility for larger molecules

• Excellent for peptides, natural products, and large aromatic compounds

• Useful for separation of large positional isomers and structurally related analytes

• 150 mm length provides increased resolution and peak capacity

• Compatible with most standard HPLC systems

• Ideal for method development and routine large-molecule separations