HPLC Column, RP Phenyl, 5um, 2.1mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl™ HPLC Columns are designed for reversed-phase separations where aromatic selectivity is beneficial. Manufactured using ultra-high purity silica bonded with a three-carbon linker and terminal phenyl functionality, this stationary phase is fully double end-capped to minimize secondary interactions and provide highly reproducible chromatographic performance. RP Phenyl™ is an excellent alternative for USP L11 methods and is commonly selected for both established methods and new method development, including LC-MS applications.
68524-10P-2 is packed with 5 µm RP Phenyl™ particles featuring a 100 Å pore size in a 2.1 mm ID x 100 mm format. The narrow internal diameter reduces solvent consumption while maintaining the aromatic selectivity and retention characteristics expected from a phenyl stationary phase. The 100 mm length provides greater chromatographic resolution than shorter columns while maintaining reasonable run times and lower operating backpressure than longer column formats.
The 2.1 mm ID x 100 mm format is particularly well suited for LC-MS applications, positional isomer separations, pharmaceutical analysis, and method development when additional separation is required. Typical flow rates are approximately 0.2-0.3 mL/min. Standard HPLC systems used with 2.1 mm ID columns must be capable of delivering stable and reproducible low flow rates, and detector flow cells should be optimized for reduced flow rates and lower internal volumes to achieve optimum performance.
Key Benefits
RP Phenyl™ stationary phase
USP L11 equivalent chemistry
Ultra-high purity silica support
Fully double end-capped
Phenyl bonded phase
100 Å pore size
Suitable for reversed-phase HPLC
Enhanced aromatic selectivity
Reduced solvent consumption
Excellent for LC-MS applications
Typical Applications
Positional isomer separations
LC-MS methods
Tocopherol analysis
Flavonoid analysis
Polynuclear aromatic hydrocarbon analysis
Nitro-aromatic compound analysis
Active pharmaceutical ingredient (API) analysis
Natural product analysis
Pharmaceutical method development
Reversed-phase HPLC
Specifications
Product Type: HPLC Column
Stationary Phase: RP Phenyl™
Chromatography Mode: Reversed Phase
USP Classification: L11
Particle Size: 5 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 100 mm
Recommended Flow Rate: 0.2-0.3 mL/min
Column Hardware: Stainless Steel
Brand: Cogent
Important Notes
Suitable for reversed-phase chromatography
USP L11 equivalent chemistry
Fully double end-capped stationary phase
Excellent selectivity for aromatic compounds
Useful for separation of positional isomers and structurally similar analytes
Commonly used for tocopherols, flavonoids, APIs, and natural products
100 mm length provides enhanced resolution compared to 50 mm columns
Ideal for LC-MS applications where additional separation is required
Standard HPLC systems must be capable of reliable low-flow operation at approximately 0.2-0.3 mL/min
Detector flow cells should be optimized for low-volume applications