Semi Prep Guard Column Cartridge, RP C18, 5um, 100A. 10mm ID x 10mm Length. Cogent Brand. 5/PK.
Additional Info:
The 68518‑SP‑PG1 Cogent RP C18 Guard Column Cartridges are designed to protect your semi‑preparative HPLC column, extending column life and maintaining consistent chromatographic performance.
Packed with 5 µm Cogent RP C18™ stationary phase, and manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, these cartridges are fully double end‑capped to provide:
Reduced silanol interactions
Improved peak shape for polar and basic analytes
Consistent chromatographic protection
Constructed in stainless steel tubes with stainless steel frits, these guard cartridges are built for durability and reproducible performance in demanding applications.
Purpose of Guard Columns
Protect analytical and semi‑prep columns from:
Particulate contamination
Strongly retained compounds
Matrix interferences
Extend column lifetime
Maintain consistent retention and peak shape
Reduce downtime and replacement costs
10 mm ID – Semi‑Preparative Compatibility
Designed for semi‑preparative (10 mm ID) HPLC columns
Supports higher sample loading workflows
Maintains performance consistency in scale‑up and preparative methods
⚠️ Requires use with a 10 mm ID prep column holder system (sold separately)
Why Choose RP C18 Guard Cartridges (5 µm)
Matched Stationary Phase Protection
Same C18 chemistry as the analytical/semi‑prep column
Ensures no change in selectivity
Maintains method integrity
Reliable Hydrophobic Retention
Suitable for hydrophobic and neutral compounds
Effective with long‑chain fatty acids and similar analytes
Method Compatibility
Ideal for USP L1 methods
Supports routine analytical and semi‑prep workflows
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Reduces secondary interactions
Improves peak symmetry
Provides consistent protection for sensitive analyses
High Purity Silica
Reliable chromatographic performance
Reproducible results from cartridge to cartridge
Durable Construction
Stainless steel housing and frits
Designed for repeat use in demanding environments
Typical Applications
Semi‑preparative HPLC workflows
Column protection in method development
Pharmaceutical and QC analysis
Complex sample matrices
Hydrophobic compound separations
USP L1 reversed‑phase methods
Important Usage Notes
Designed for semi‑prep column protection (10 mm ID systems)
Must be used with a compatible guard column holder
Replace regularly to maintain optimal column performance
Helps prevent premature column degradation
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable