Process HPLC Column, RP C18, 5um, 100A. 50mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Info:
The 68518‑P50‑150 Cogent RP C18 Process HPLC Column is engineered for high‑resolution industrial purification and process chromatography development, utilizing 5 µm particles and fully double end‑capped C18 bonding to deliver extreme loading capacity, consistent retention, and reliable chromatographic performance at manufacturing scale.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this stationary phase provides:
Complete end‑capping to minimize silanol interactions
Improved peak symmetry for polar and basic analytes
Reproducible performance across large‑volume and continuous purification processes
This column is ideal as a USP L1 alternate and as a high‑performance platform for scaling purification workflows into full industrial production.
150 mm Length – Maximum Resolution for Process Purification
Higher resolving power than 50 mm and 100 mm process columns
Maximizes peak capacity for complex mixtures
Ideal for closely related compounds and difficult separations
Preferred for final process optimization before large‑batch production
Longer run times compared to shorter column formats
This configuration is selected when maximum separation performance is required prior to full‑scale manufacturing or continuous processing.
50 mm ID – Industrial‑Scale Loading Capacity
Provides extremely high sample loading capacity (beyond prep and production scale)
Designed for industrial purification and manufacturing workflows
Supports ultra‑high‑flow chromatography systems
Typical Flow Rate Range
~50–150 mL/min (system dependent)
Optimize based on process requirements and system capability
✅ Designed for process HPLC systems with ultra‑high flow rates and very large injection volumes
Flow Rate & System Considerations (50 mm ID, 5 µm)
Requires systems capable of:
Ultra‑high flow rates
Very large injection volumes
Compatible with:
Process chromatography systems
Industrial pumps and injection platforms
Large‑volume fraction collection or continuous processing systems
⚠️ Not suitable for analytical, semi‑prep, or standard preparative HPLC systems
Why Choose RP C18 (5 µm, Process Scale)
Maximum Resolution at Industrial Scale
Ideal for final purification of complex mixtures in manufacturing
Maximizes separation performance and product purity
Supports high‑purity process workflows
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Effective for lipids and long‑chain fatty acids
Provides greater retention than C8 phases
USP Method Compatibility
Suitable for USP L1 methods
Reliable for regulated industrial and pharmaceutical environments
Supports method transfer across all HPLC scales
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Stabilizes chromatography at large process scale
High Purity Silica
Consistent chromatographic performance
Reduced variability across industrial production batches
Durable & Cost‑Efficient
Long column lifetime
Designed for continuous, high‑load process workflows
Reduces downtime and operational cost
Typical Applications
Process‑scale purification
Industrial manufacturing workflows
High‑purity compound isolation
Pharmaceutical production
Process development and optimization
USP L1 reversed‑phase methods
Important Usage Notes
Designed for 50 mm ID process‑scale HPLC systems
Requires ultra‑high‑flow capability and very large sample loading volumes
Ideal for maximum‑resolution process purification workflows
Optimize for resolution vs throughput based on manufacturing goals
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable