Prep Guard Column Cartridge, RP C18, 5um, 100A. 21.2mm ID x 10mm Length. Cogent Brand. 1 EA.
Additional Info:
The 68518‑P21‑PG1 Cogent RP C18 Prep Guard Column Cartridge is designed to protect high‑value preparative HPLC columns, extending column life while maintaining consistent chromatographic performance.
Packed with 5 µm Cogent RP C18™ stationary phase, and manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this cartridge is fully double end‑capped to provide:
Reduced silanol interactions
Improved peak shape for polar and basic analytes
Reliable and reproducible chromatographic protection
Constructed in a stainless steel housing with stainless steel frits, this guard cartridge ensures durability in demanding preparative environments.
Purpose of Guard Columns
Protect preparative columns from:
Particulate contamination
Strongly retained compounds
Sample matrix buildup
Extend column lifetime
Maintain consistent retention and peak shape
Reduce downtime and replacement costs
21.2 mm ID – Preparative Scale Compatibility
Designed for 21.2 mm ID preparative HPLC columns
Supports high‑flow, high‑load purification workflows
Maintains performance in large‑scale separations
⚠️ Requires a 21.2 mm ID prep column holder system
Why Choose RP C18 Guard Cartridges (5 µm, Prep Scale)
Matched Stationary Phase Protection
Same C18 chemistry as the prep column
Maintains selectivity and method integrity
Prevents changes in chromatographic behavior
High‑Load Protection
Designed to handle large injection volumes and high sample loads
Protects columns during purification and scale‑up workflows
Method Compatibility
Suitable for USP L1 methods
Supports preparative and semi‑prep chromatography workflows
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Stabilizes chromatographic performance
High Purity Silica
Consistent performance across cartridges
Reliable protection over extended use
Durable Construction
Stainless steel housing and frits
Designed for high‑flow preparative systems
Typical Applications
Preparative HPLC workflows
Column protection during purification
High‑load separations
Pharmaceutical and QC processes
Hydrophobic and neutral compound purification
USP L1 reversed‑phase methods
Important Usage Notes
Designed for preparative HPLC systems (21.2 mm ID)
Must be used with a compatible prep guard column holder
Replace regularly to maintain optimal column performance
Essential for protecting high‑value preparative columns
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable