CUSTOM ITEM: HPLC Column, RP C18, 5um, 4.0mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68518‑15P‑4 Cogent RP C18 HPLC Column is designed for maximum‑resolution analytical separations, featuring 5 µm particles and fully double end‑capped C18 bonding to deliver reliable retention, excellent peak shape, and consistent performance.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this stationary phase provides:
Complete end‑capping to minimize silanol interactions
Improved peak symmetry for polar and basic analytes
Consistent and reproducible chromatography
This column is widely used as a primary analytical column, a starting point for new methods, and as an alternate for USP L1 methods using 5 µm particle phases.
150 mm Length – Maximum Resolution
Highest resolving power in the 4.0 mm RP C18 range
Maximizes peak capacity for complex mixtures
Ideal for closely related compounds and difficult separations
Preferred for final method optimization and high‑purity analysis
Longer run times compared to 50 mm and 100 mm formats
This column is selected when maximum separation performance is required over speed.
4.0 mm ID – Solvent‑Saving Analytical Performance
Comparable chromatographic behavior to 4.6 mm ID columns
Reduces mobile phase consumption and waste
Typical flow rate range: ~0.8–1.2 mL/min
Optimal starting range: ~0.85–1.10 mL/min
Benefits:
Lower solvent usage
Reduced operating cost
Compatible with standard HPLC systems
Flow Rate & System Considerations (4.0 mm ID, 5 µm)
Suitable for conventional HPLC systems
Supports higher flow rates compared to smaller particle sizes
Well suited for:
Viscous mobile phases
Longer gradients
Routine and extended analytical runs
Why Choose RP C18 (5 µm)
Robust & Reliable Operation
Ideal for routine analytical workflows
Lower backpressure relative to smaller particle sizes
Suitable for long method lifetimes and consistent results
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids
Provides greater retention than C8 phases
Method Development & USP Compatibility
Ideal for new method development and optimization
Suitable for USP L1 methods using 5 µm particles
Reliable alternate or replacement column
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Better performance for basic analytes
High Purity Silica
Consistent chromatographic performance
Reduced variability across runs
Durable & Cost‑Efficient
Long column lifetime
Reduced system strain
Lower maintenance frequency
Typical Applications
Pharmaceutical and QC analysis
Hydrophobic and neutral compound separations
Long‑chain fatty acids
Complex analytical methods
Method development and validation
USP L1 reversed‑phase workflows
Important Usage Notes
Compatible with standard HPLC systems
Ideal for maximum‑resolution analytical methods
Best suited when complex separations require high peak capacity
Optimize flow rate and mobile phase for desired resolution vs run time balance
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable