HPLC Column, RP C18, 5um, 2.1mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68518‑05P‑2 Cogent RP C18 HPLC Column is a robust, reversed‑phase column featuring 5 µm particles and fully double end‑capped C18 bonding, delivering reliable retention, excellent durability, and consistent chromatographic performance.
Manufactured using high‑purity silica and traditional octadecylsilane (C18) bonding, this stationary phase:
Uses complete end‑capping to minimize silanol interactions
Improves peak shape for polar and basic analytes
Provides consistent and reproducible analytical results
This column is ideal as a USP L1 alternate column and a dependable choice for routine analytical methods.
50 mm Length – Fast Analysis & Throughput
Designed for rapid separations and short run times
Lower backpressure compared to longer columns
Ideal for high‑throughput workflows and screening
Frequently used in LC‑MS methods requiring fast cycle times
Flow Rate & System Requirements (2.1 mm ID, 5 µm)
Typical flow rate range: ~0.2–0.5 mL/min
Optimal starting range: ~0.25–0.40 mL/min
Requires:
HPLC system capable of stable low‑flow delivery
Low‑volume detector flow cell
Reliable injection system
✅ This column operates under standard HPLC high‑pressure conditions ✅ Produces lower backpressure than 3 µm and 1.8 µm columns, but is still firmly within high‑pressure HPLC operation
Why Choose RP C18 (5 µm)
High‑Pressure Robustness & Reliability
Designed for standard high‑pressure HPLC systems
Lower backpressure compared to smaller particles
Ideal for rugged, long‑term analytical methods
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids
Provides longer retention than C8 phases
USP Method Compatibility
Suitable for USP L1 methods using 5 µm columns
Reliable alternate or replacement column
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Reduces secondary interactions
Improves peak symmetry
Enhances performance for basic analytes
High Purity Silica
Consistent results across runs
Excellent reproducibility
Durable & Cost‑Efficient
Longer column lifetime compared to smaller particles
Reduced system stress vs higher efficiency media
Lower maintenance frequency
Typical Applications
LC‑MS analytical workflows
Pharmaceutical and QC analysis
Hydrophobic and neutral compound separations
Long‑chain fatty acids
Routine analytical HPLC methods
USP L1 reversed‑phase methods
Important Usage Notes
Operates under standard high‑pressure HPLC conditions
Requires stable low‑flow system performance (2.1 mm ID)
Ideal for rugged, repeatable methods
Chosen when robustness and system compatibility are prioritized over maximum efficiency