HPLC Column, RP Phenyl, Wide Pore, 3um, 4.6mm ID x 150mm Length, 300A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl™ Wide Pore is a reversed-phase HPLC stationary phase designed to provide unique selectivity through π-π interactions between aromatic analytes and the bonded phenyl functionality while offering enhanced accessibility for larger molecules. Manufactured using a traditional three-carbon linker with a terminal phenyl ring bonded to ultra-high purity silica and fully double end capped, this 300 Å wide pore phase provides chromatographic behavior distinct from conventional alkyl phases. As a USP L11 equivalent phase, it is particularly useful for large molecules, aromatic compounds, natural products, peptides, and method development applications.
68324-15P-3M is an HPLC column packed with 3 µm RP Phenyl™ Wide Pore particles featuring a 300 Å pore size in a 4.6 mm ID x 150 mm format. The 150 mm length provides increased chromatographic resolution and peak capacity compared to shorter column formats, while the 3 µm particles provide greater efficiency and sharper peaks than comparable 5 µm columns. The wide pore structure improves analyte access to the bonded phase for larger compounds while maintaining the distinctive selectivity associated with phenyl chemistry. Typical operating flow rates are approximately 0.8–1.5 mL/min depending on mobile phase composition, temperature, and system configuration.
This column is particularly useful for the separation of large positional isomers, natural products, related compounds, and certain peptides in reversed-phase HPLC. The unique selectivity of the phenyl phase can provide improved resolution for aromatic analytes where conventional C8 or C18 phases may not deliver adequate selectivity. The combination of wide pores, enhanced aromatic selectivity, and increased resolving power makes this column an excellent choice for demanding pharmaceutical, bioanalytical, and research applications.
Key Benefits
RP Phenyl™ Wide Pore stationary phase
USP L11 equivalent chemistry
Fully double end capped
Phenyl bonded phase
Ultra-high purity silica support
300 Å wide pore design
Enhanced aromatic selectivity
Optimized for larger molecules
3 µm particle size
Increased chromatographic resolution
Typical Applications
USP L11 methods
Large positional isomer separations
Natural product analysis
Peptide analysis
Aromatic compound analysis
Method development
Bioanalytical methods
Pharmaceutical analysis
Reversed-phase HPLC
Research and development
Specifications
Product Type: HPLC Column
Stationary Phase: RP Phenyl™ Wide Pore
USP Classification: L11
Chromatography Mode: Reversed Phase
Bonded Phase: Phenyl
Endcapping: Fully Double End Capped
Particle Size: 3 µm
Pore Size: 300 Å
Column Dimensions: 4.6 mm ID x 150 mm
Length: 150 mm
Typical Flow Rate: 0.8–1.5 mL/min
Brand: Cogent
Important Notes
Designed for larger molecules and aromatic compounds
300 Å wide pores improve access to the bonded phase for larger analytes
Suitable for conventional HPLC systems
3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns
Generates higher backpressure than larger particle columns
The 150 mm length provides greater resolution and peak capacity than shorter column formats
Particularly useful for peptides, natural products, and larger aromatic analytes
Provides unique selectivity compared to C8 and C18 phases
Commonly used as an alternative for USP L11 methods involving larger analytes
Well suited for demanding analytical and bioanalytical separations