HPLC Column, RP Phenyl, 3um, 2.1mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent RP Phenyl™ is a reversed-phase HPLC stationary phase designed to provide unique selectivity through π-π interactions between aromatic analytes and the bonded phenyl functionality. Manufactured using a traditional three-carbon linker with a terminal phenyl ring bonded to ultra-high purity silica and fully double end capped, this stationary phase provides chromatographic behavior distinct from conventional alkyl phases. As a USP L11 equivalent phase, it is widely used for method replacement, method development, and applications involving aromatic and structurally related compounds.
68324-15P-2 is an HPLC column packed with 3 µm RP Phenyl™ particles featuring a 100 Å pore size in a 2.1 mm ID x 150 mm format. This narrow-bore configuration combines maximum chromatographic resolution with reduced solvent consumption and excellent compatibility with LC-MS instrumentation. The 150 mm length provides significantly greater peak capacity and resolving power than shorter column formats, while the 3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns. Typical operating flow rates are approximately 0.2–0.3 mL/min. Because of the low flow rates required by 2.1 mm ID columns, standard HPLC systems must be capable of precise and reproducible low-flow operation.
This column is particularly useful for the separation of positional isomers, tocopherols, flavonoids, polynuclear aromatic hydrocarbons, nitro-aromatic compounds, active pharmaceutical ingredients (APIs), natural products, and related compounds. The unique selectivity of the phenyl phase makes it an excellent choice when conventional C18 or C8 columns do not provide adequate resolution. This column format is especially well suited for LC-MS applications where increased separation, enhanced peak capacity, and reduced solvent consumption are desired.
Key Benefits
RP Phenyl™ stationary phase
USP L11 equivalent chemistry
Fully double end capped
Phenyl bonded phase
Ultra-high purity silica support
Enhanced aromatic selectivity
Excellent isomer separation capability
3 µm particle size
Greater efficiency than 5 µm columns
Excellent for LC-MS applications
Typical Applications
USP L11 methods
LC-MS methods
Positional isomer separations
Tocopherol analysis
Flavonoid analysis
Polynuclear aromatic hydrocarbon analysis
Nitro-aromatic compound analysis
Active pharmaceutical ingredient (API) analysis
Natural product analysis
Method development
Specifications
Product Type: HPLC Column
Stationary Phase: RP Phenyl™
USP Classification: L11
Chromatography Mode: Reversed Phase
Bonded Phase: Phenyl
Endcapping: Fully Double End Capped
Particle Size: 3 µm
Pore Size: 100 Å
Column Dimensions: 2.1 mm ID x 150 mm
Length: 150 mm
Typical Flow Rate: 0.2–0.3 mL/min
Brand: Cogent
Important Notes
Suitable for conventional HPLC and LC-MS systems
3 µm particles provide higher efficiency and sharper peaks than comparable 5 µm columns
Generates higher backpressure than larger particle columns
The 2.1 mm ID format is commonly used for LC-MS applications
Standard HPLC systems must be capable of precise and reproducible operation at approximately 0.2–0.3 mL/min
Detector flow cells should be optimized for low-volume, narrow-bore chromatography
The 150 mm length provides maximum resolution and peak capacity for complex separations
Provides unique selectivity compared to C8 and C18 phases
Particularly useful for aromatic compounds and positional isomers
Commonly used as an alternative for USP L11 methods