HPLC Column, RP C18, 3um, 4.6mm ID x 150mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68318‑15P Cogent RP C18 HPLC Column is engineered for maximum‑resolution analytical separations, featuring 3 µm particles and fully double end‑capped C18 bonding to provide high efficiency, excellent peak shape, and consistent performance.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) chemistry, this stationary phase offers:
Complete end‑capping to minimize silanol interactions
Improved peak shape for polar and basic analytes
Robust and reproducible performance across applications
This column is widely used as a primary analytical column and as a USP L1 alternate, trusted for both routine and advanced method development.
150 mm Length – Maximum Resolution & Peak Capacity
Highest resolving power in the 4.6 mm RP C18 column range
Maximizes separation of closely related compounds
Ideal for complex mixtures and demanding analytical methods
Preferred when maximum resolution is required over speed
Longer run times compared to 50 mm and 100 mm formats
4.6 mm ID – Standard Analytical Performance
Industry‑standard HPLC column dimension
Compatible with all conventional HPLC systems
Typical flow rate range: ~0.8–1.5 mL/min
Optimal starting range: ~1.0–1.2 mL/min
Provides:
Strong detector response
Excellent reproducibility
Easy method transfer between instruments
Why Choose RP C18 (3 µm)
Balanced Efficiency & Pressure
More efficient than 5 µm columns
Lower backpressure than 1.8 µm UHPLC columns
Ideal balance between performance and system compatibility
Reliable Hydrophobic Retention
Strong retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids and similar analytes
Versatile Method Development
Suitable for new method development
Widely used across industries
Compatible with USP L1 method substitution
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Enhances performance for basic compounds
High Carbon Load
Increased retention and loading capacity
Greater method flexibility
Low Column Bleed
Ideal for sensitive detection techniques (LC‑MS and UV)
Clean baselines and accurate results
High Purity Silica
Consistent, reproducible chromatography
Reduced variability between columns and runs
Typical Applications
Pharmaceutical and QC analysis
Hydrophobic and neutral compound separations
Long‑chain fatty acids
Complex mixture separations
Method development and validation
USP L1 reversed‑phase methods
Important Usage Notes
Compatible with standard HPLC systems
Monitor pressure for viscous solvents or extended methods
Ideal when maximum resolution is required
Best suited for complex separations where shorter columns are insufficient