CUSTOM ITEM: HPLC Column, RP C18, 3um, 4.0mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68318‑10P‑4 Cogent RP C18 HPLC Column is a high‑performance, solvent‑saving reversed‑phase column featuring 3 µm particles and fully double end‑capped C18 bonding, providing improved efficiency, consistent retention, and reliable analytical results.
Manufactured with high‑purity silica and traditional octadecylsilane (C18) chemistry, this stationary phase:
Uses complete end‑capping to minimize silanol interactions
Improves peak shape for polar and basic analytes
Provides excellent reproducibility and robustness
This column is ideal as both a primary analytical column and as an alternate for USP L1 methods requiring 3 µm particle columns.
100 mm Length – Increased Resolution
Higher resolving power compared to 50 mm columns
Improved peak capacity and separation of closely related analytes
Ideal when short columns do not provide sufficient resolution
Balanced performance between analysis time and separation quality
4.0 mm ID – Solvent‑Saving Analytical Performance
Comparable performance to 4.6 mm ID columns
Reduced mobile phase consumption and waste
Typical flow rate range: ~0.8–1.2 mL/min
Optimal starting range: ~0.9–1.1 mL/min
Benefits:
Lower operating cost
Maintains strong detector response
Compatible with standard HPLC systems
Why Choose RP C18 (3 µm)
Balanced Efficiency & Pressure
Higher efficiency than 5 µm columns
Lower backpressure than sub‑2 µm UHPLC columns
Ideal balance of performance and system compatibility
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids and similar analytes
USP Method Compatibility
Suitable for USP L1 methods using 3 µm phases
Valuable as an alternate or replacement column
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Reduces secondary interactions
Improves peak symmetry
Better performance for basic analytes
High Purity Silica
Consistent results across runs
Reduced variability between columns
Cost‑Efficient Operation
Lower pressure requirements than UHPLC columns
Reduced solvent consumption vs larger ID columns
Lower cost per analysis
Typical Applications
Pharmaceutical and QC analysis
Hydrophobic and neutral compound separations
Long‑chain fatty acids
Method development and validation
Routine reversed‑phase HPLC workflows
USP L1 analytical methods
Important Usage Notes
Compatible with standard HPLC systems
Monitor pressure when using viscous solvents or extended run conditions
Ideal for applications requiring improved resolution without UHPLC systems
Suitable for routine and development workflows
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable