CUSTOM ITEM: HPLC Column, RP C18, 3um, 4.0mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68318‑05P‑4 Cogent RP C18 HPLC Column is a high‑value, fully end‑capped reversed‑phase column designed to deliver consistent retention, improved efficiency, and reliable performance for a wide range of analytical methods.
Manufactured with high‑purity silica and traditional octadecylsilane (C18) bonding, this stationary phase:
Uses full double end‑capping to minimize silanol interactions
Improves peak shape for polar and basic analytes
Provides excellent reproducibility across methods
This column is widely used as both a primary analytical column and as an alternate choice for USP L1 methods using 3 µm particle columns.
50 mm Length – Fast Analysis & Throughput
Designed for short run times and rapid separations
Lower backpressure compared to longer columns
Ideal for high‑throughput workflows and screening
Efficient for method development and optimization
4.0 mm ID – Solvent‑Saving Analytical Performance
Provides performance similar to 4.6 mm ID columns
Reduces mobile phase consumption and waste
Typical flow rate range: ~0.8–1.2 mL/min
Optimal starting range: ~0.9–1.1 mL/min
Benefits:
Lower operating cost compared to 4.6 mm columns
Maintains strong detector response
Compatible with standard HPLC systems
Why Choose RP C18 (3 µm)
Balanced Efficiency & Pressure
Higher efficiency than 5 µm columns
Lower backpressure than sub‑2 µm UHPLC columns
Ideal balance between performance and system compatibility
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids and similar analytes
USP Method Compatibility
Suitable for USP L1 methods requiring 3 µm particles
Valuable as an alternate or replacement column
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Reduces secondary interactions
Improves peak symmetry
Better performance for basic compounds
High Purity Silica
Consistent chromatography
Reduced variability between runs
Cost‑Efficient Operation
Lower solvent usage vs larger ID columns
Reduced pressure demands vs UHPLC columns
Lower cost per analysis
Typical Applications
Pharmaceutical and QC analysis
Hydrophobic and neutral compound separations
Long‑chain fatty acids
Method development and validation
Routine reversed‑phase HPLC workflows
USP L1 analytical methods
Important Usage Notes
Compatible with standard HPLC systems
Monitor pressure when using viscous solvents or longer methods
Ideal balance between efficiency and system compatibility
Recommended for labs seeking reliable performance with reduced solvent use
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable