UHPLC Column, RP C18, 1.8um, 100A. 2.1mm ID x 150mm Length. Cogent Brand. 1 EA.
Additional Info:
The 68118‑15P‑2 Cogent RP C18 UHPLC Column is engineered for maximum resolution and peak capacity, using 1.8 µm particles and fully double end‑capped C18 bonding to deliver high‑efficiency, reproducible separations.
Manufactured with high‑purity silica and traditional octadecylsilane (C18) bonding, this column provides:
Complete end‑capping to reduce silanol activity
Improved peak symmetry for polar and basic analytes
High reproducibility and method robustness
This column is ideal for complex separations where maximum resolving power is required.
150 mm Length – Maximum Resolution for LC‑MS
Highest resolving power in the 2.1 mm RP C18 range
Maximizes peak capacity and separation of complex mixtures
Ideal for samples with a large number of peaks and diverse compounds
Preferred for LC‑MS workflows requiring detailed resolution
Longer run times compared to 50 mm and 100 mm formats
This format is commonly used when maximum analytical performance outweighs speed.
Flow Rate & System Requirements (2.1 mm ID, 1.8 µm)
⚠️ Requires UHPLC system capability due to high backpressure
Typical flow rate range: ~0.2–0.4 mL/min
Optimal starting range: ~0.18–0.30 mL/min for maximum resolution
Requires:
UHPLC system capable of high‑pressure operation
Low‑volume detector flow cell
Accurate and stable low‑flow pumping
✅ Sample preparation requirement: use a 0.2 µm syringe filter to prevent clogging and maintain column performance
⚠️ Standard HPLC systems may not support required pressures or low‑flow precision.
Why Choose RP C18 for UHPLC
Maximum Efficiency & Peak Capacity
1.8 µm particles deliver exceptional plate counts
Highest peak capacity among standard particle sizes
Ideal for resolving complex, multi‑component samples
Reliable Hydrophobic Retention
Strong retention for hydrophobic and neutral compounds
Predictable reversed‑phase chromatographic behavior
Versatile Method Development Platform
Widely applicable across industries
Ideal for new method development and optimization
Easily scaled to different column lengths and IDs
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Reduced secondary interactions
Improved peak symmetry
Better performance for basic compounds
High Purity Silica
Consistent and reproducible results
Reduced column‑to‑column variability
Efficient UHPLC Operation
Higher throughput despite longer column length
Improved resolution without sacrificing method reliability
Reduced solvent consumption with 2.1 mm format
Typical Applications
LC‑MS workflows requiring maximum resolution
Pharmaceutical and bioanalytical analysis
Complex mixture separations
Hydrophobic and neutral compound analysis
Method development for challenging analytes
Important Usage Notes
Requires UHPLC system capable of high pressure
Use 0.2 µm filtration to protect column lifetime
Ideal for high‑complexity separations with many analytes
Best suited when maximum resolution is required over speed