Semi Prep Guard Column Cartridge, RP C18, 10um, 100A. 10mm ID x 10mm Length. Cogent Brand. 5/PK.
Additional Info:
The 68018‑SP‑PG1 Cogent RP C18 Guard Column Cartridges are designed to extend the life and maintain the performance of semi‑preparative HPLC columns, utilizing 10 µm Cogent RP C18™ stationary phase with fully double end‑capped bonding for reliable and consistent chromatographic protection.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, these cartridges provide:
Reduced silanol interactions
Improved peak shape for polar and basic analytes
Consistent and reproducible column protection
Constructed in stainless steel tubes with stainless steel frits, these cartridges ensure durability and reliable operation in semi‑prep environments.
Purpose of Guard Columns
Protect columns from:
Particulate contamination
Strongly retained compounds
Sample matrix buildup
Extend column lifetime
Maintain consistent retention and peak shape
Reduce downtime and replacement costs
10 µm Guard Media – Preparative Compatibility
Matches 10 µm preparative/semi‑prep column packing
Supports higher sample loading workflows
Ideal for scale‑up and purification applications
✅ Maintains consistent selectivity with prep‑scale columns
10 mm ID – Semi‑Preparative Systems
Designed for 10 mm ID semi‑prep HPLC columns
Supports higher flow rates and loading volumes
Maintains protection in purification workflows
⚠️ Requires use with a 10 mm ID prep/guard column holder system
Why Choose RP C18 Guard Cartridges (10 µm)
Matched Stationary Phase Protection
Same C18 chemistry as the column being protected
Maintains method integrity and selectivity
Prevents changes in chromatographic behavior
Ideal for High‑Load Applications
Handles larger sample loads typical of semi‑prep workflows
Protects columns during purification and scale‑up methods
Method Compatibility
Suitable for USP L1 methods
Reliable for routine and preparative chromatography workflows
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Stabilizes chromatographic performance
High Purity Silica
Consistent performance across cartridges
Reliable protection from injection to injection
Durable Construction
Stainless steel housing and frits
Designed for repeated use in demanding environments
Typical Applications
Semi‑preparative HPLC workflows
Column protection during purification
Method development and optimization
Hydrophobic and neutral compound separations
Pharmaceutical and QC applications
USP L1 reversed‑phase methods
Important Usage Notes
Designed for semi‑prep column protection (10 mm ID systems)
Must be used with a compatible guard column holder
Replace regularly to maintain optimal performance
Essential for protecting high‑value semi‑prep columns
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable