Process HPLC Column, RP C18, 10um, 100A. 50mm ID x 50mm Length. Cogent Brand. 1 EA.
Additional Info:
The 68018‑P50‑50 Cogent RP C18 Process HPLC Column is designed for industrial‑scale purification and process chromatography development, utilizing 10 µm particles and fully double end‑capped C18 bonding to deliver maximum durability, extremely high loading capacity, and reliable chromatographic performance under continuous operation.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this stationary phase provides:
Complete end‑capping to minimize silanol interactions
Improved peak symmetry for polar and basic analytes
Consistent and reproducible performance in large‑volume purification workflows
This column is ideal as a USP L1 alternate and as a robust starting platform for process‑scale and manufacturing chromatography workflows.
50 mm Length – Fast Process Scouting & Throughput Optimization
Designed for rapid separations and short cycle times
Ideal for early‑stage process method development
Minimizes solvent usage during large‑scale screening
Enables high‑throughput purification and process optimization
50 mm ID – Maximum Industrial‑Scale Loading
Provides extremely high sample loading capacity (top tier across entire column system)
Designed for industrial purification, manufacturing workflows, and continuous processing
Supports ultra‑high‑flow chromatography systems
Typical Flow Rate Range
~50–150 mL/min (system dependent)
Optimize based on process requirements and system capability
✅ Designed for process HPLC systems capable of ultra‑high flow rates and very large injection volumes
Flow Rate & System Considerations (50 mm ID, 10 µm)
Requires systems capable of:
Ultra‑high flow rates
Very large injection volumes
Compatible with:
Process chromatography systems
Industrial pumps and injection platforms
Large‑volume fraction collection or continuous processing systems
⚠️ Not suitable for analytical, semi‑prep, or standard preparative HPLC systems
Why Choose RP C18 (10 µm, Process Scale)
Ideal for Process Scouting & Scale‑Up
Used for developing and optimizing purification workflows prior to full production deployment
Enables efficient transition to longer columns and continuous manufacturing systems
Supports consistent analytical → semi‑prep → prep → production → process workflows
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Effective for lipids and long‑chain fatty acids
Provides greater retention than C8 phases
USP Method Compatibility
Suitable for USP L1 methods
Reliable for validated industrial and pharmaceutical environments
Supports method transfer across all HPLC scales
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Enhances robustness under high‑load process conditions
High Purity Silica
Consistent chromatographic performance
Reduced variability across large‑scale and continuous runs
Durable & Cost‑Efficient
Long column lifetime
Designed for high‑load industrial workflows
Reduces downtime and maintenance costs
Typical Applications
Industrial‑scale purification
Process chromatography development
High‑throughput compound isolation
Pharmaceutical manufacturing
Continuous processing systems
USP L1 reversed‑phase methods
Important Usage Notes
Designed for 50 mm ID process‑scale HPLC systems
Requires ultra‑high‑flow capability and very large sample loading volumes
Ideal for fast screening prior to high‑purity production workflows
Choose when durability, throughput, and loading capacity are prioritized over efficiency
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable