CUSTOM ITEM: HPLC Column, RP C18, 10um, 4.0mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.
Additional Info:
The 68018‑05P‑4 Cogent RP C18 HPLC Column is designed for method development and preparative scouting, utilizing 10 µm particles and fully double end‑capped C18 bonding to provide reliable retention, excellent durability, and consistent chromatographic performance.
Manufactured using high‑purity silica with traditional octadecylsilane (C18) bonding, this stationary phase provides:
Complete end‑capping to minimize silanol interactions
Improved peak symmetry for polar and basic analytes
Consistent and reproducible chromatography
This column is ideal as a USP L1 alternate and as a scouting platform for scaling analytical methods to preparative applications.
50 mm Length – Fast Method Development
Designed for rapid separations and short run times
Ideal for early‑stage method screening and optimization
Minimizes solvent usage during development
Excellent for high‑throughput method scouting workflows
4.0 mm ID – Solvent‑Saving Analytical Format
Comparable chromatographic behavior to 4.6 mm ID columns
Reduces mobile phase consumption and waste
Typical flow rate range: ~0.8–1.2 mL/min
Optimal starting range: ~0.9–1.1 mL/min
Benefits:
Lower solvent cost
Reduced waste generation
Compatible with standard HPLC systems
Flow Rate & System Considerations (4.0 mm ID, 10 µm)
Suitable for standard HPLC systems
Supports higher flow rates relative to smaller particle sizes
Well suited for:
Preparative method development
Sample loading studies
Robust screening workflows
Why Choose RP C18 (10 µm)
Ideal for Preparative Scouting
Commonly used to develop and optimize methods prior to preparative scale‑up
Predictable selectivity for method transfer to larger ID columns
Supports efficient scaling from analytical to prep workflows
Reliable Hydrophobic Retention
Strong reversed‑phase retention for hydrophobic and neutral compounds
Excellent for long‑chain fatty acids
Provides greater retention than C8 phases
Method Development & USP Compatibility
Suitable for USP L1 methods
Ideal starting point for new analytical or preparative methods
Reliable and consistent phase chemistry
Cogent RP C18™ Advantages
Fully End‑Capped Surface
Minimizes secondary interactions
Improves peak symmetry
Enhances performance for basic analytes
High Purity Silica
Consistent chromatographic performance
Reduced variability between runs
Durable & Cost‑Efficient
Long column lifetime
Ideal for repeated method development cycles
Reduced maintenance frequency
Typical Applications
Preparative method scouting
Method development and optimization
Hydrophobic and neutral compound separations
Long‑chain fatty acids
Analytical to preparative scale‑up workflows
USP L1 reversed‑phase methods
Important Usage Notes
Designed for method development and preparative scaling workflows
Compatible with standard HPLC systems
Ideal for fast screening prior to method scale‑up
Choose when robustness and loading capacity are prioritized over maximum efficiency
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable