Catalog Number - 68008-SP-PG1-3

Cogent RP C8 Octyl Wide Pore Semi-Preparative Guard Column Cartridges are packed with the same high-quality stationary phase used in Cogent RP C8 Octyl Wide Pore semi-preparative columns. The 300 Å pore structure is specifically designed to improve accessibility for proteins, peptides, and other large molecules, while the fully double endcapped octyl (C8) bonded phase provides reliable chromatographic performance and effective protection for semi-preparative purification workflows.

68008-SP-PG1-3 contains five guard column cartridges packed with 10 µm RP C8 Octyl Wide Pore material featuring a 300 Å pore size in 10 mm ID x 10 mm length stainless steel hardware. Designed specifically for use with 10 mm ID semi-preparative HPLC columns, these guard cartridges help intercept particulates, strongly retained contaminants, and sample matrix components before they reach the main column. The matching stationary phase chemistry helps maintain chromatographic selectivity while protecting valuable semi-preparative columns from contamination and premature fouling.

Used in protein purification, peptide isolation, and other biomolecule purification workflows, these guard cartridges help preserve semi-preparative column efficiency, improve reproducibility, and reduce replacement costs. The stainless steel cartridge construction and stainless steel frits provide durability for routine purification, process development, and scale-up chromatography applications.

Key Benefits

• Packed with Cogent RP C8 Octyl Wide Pore stationary phase

• 300 Å pore size optimized for larger molecules

• Fully double endcapped chemistry

• Traditional octyl (C8) bonded phase

• Protects semi-preparative HPLC columns from contaminants

• Helps maintain column efficiency and reproducibility

• Extends semi-preparative column service life

• 10 µm particles for low operating backpressure

• Stainless steel cartridge construction

• Supplied as a convenient 5-pack

Typical Applications

• Semi-preparative HPLC purification

• Protein purification

• Peptide purification

• Biomolecule isolation

• Fraction collection

• Pharmaceutical research

• Biotechnology research

• Process development

• Method scale-up

• Semi-preparative column protection

Specifications

• Product Type: Semi-Preparative Guard Column Cartridges

• Stationary Phase: RP C8 Octyl Wide Pore

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double Endcapped

• Particle Size: 10 µm

• Pore Size: 300 Å

• Cartridge Dimensions: 10 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Quantity: 5/PK

• Brand: Cogent

Guard Column Holder Requirement

• A Cogent 10 mm ID Semi-Preparative Guard Column Holder is required for use with these guard cartridges.

• View the Cogent 10 mm ID Semi-Preparative Guard Column Holder (83000-SP-GH)

Important Notes

• Compatible with Cogent RP C8 Octyl Wide Pore semi-preparative HPLC columns

• Optimized for proteins, peptides, and other high molecular weight compounds

• Designed to intercept particulates and contaminants before they reach the main column

• Recommended for routine purification and scale-up workflows

• Replace guard cartridges as needed based on sample cleanliness and application requirements