Catalog Number - 68008-SP-PG1

Cogent RP C8 Octyl Semi-Preparative Guard Column Cartridges are packed with the same high-quality stationary phase used in Cogent RP C8 Octyl semi-preparative columns, featuring traditional octyl (C8) silane bonding on high-purity silica with complete double endcapping. These guard cartridges are designed to capture particulates, strongly retained contaminants, and sample matrix components before they reach the semi-preparative column, helping maintain chromatographic performance, extend column life, and reduce replacement costs.

68008-SP-PG1 contains five guard column cartridges packed with 10 µm RP C8 Octyl material featuring a 100 Å pore size in 10 mm ID x 10 mm length stainless steel hardware. Designed specifically for use with 10 mm ID semi-preparative HPLC columns, these guard cartridges provide economical protection while maintaining compatibility with purification and fraction collection workflows. The matching stationary phase chemistry helps preserve chromatographic selectivity while protecting valuable semi-preparative columns from contamination and premature fouling.

Used in semi-preparative purification, compound isolation, and fraction collection applications, these guard cartridges help preserve column efficiency, improve reproducibility, and minimize downtime. The stainless steel cartridge construction and stainless steel frits provide excellent durability for routine purification, process development, and scale-up chromatography operations.

Key Benefits

• Packed with Cogent RP C8 Octyl stationary phase

• Fully double endcapped chemistry

• Traditional octyl (C8) bonded phase

• Protects semi-preparative HPLC columns from contaminants

• Helps maintain column efficiency and reproducibility

• Extends semi-preparative column service life

• 10 µm particles for low operating backpressure

• Stainless steel cartridge construction

• Stainless steel frits

• Supplied as a convenient 5-pack

Typical Applications

• Semi-preparative HPLC purification

• Fraction collection

• Compound isolation

• Pharmaceutical research

• Synthetic chemistry

• Natural product purification

• Process development

• Method scale-up

• Production support purification

• Semi-preparative column protection

Specifications

• Product Type: Semi-Preparative Guard Column Cartridges

• Stationary Phase: RP C8 Octyl

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double Endcapped

• Particle Size: 10 µm

• Pore Size: 100 Å

• Cartridge Dimensions: 10 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Quantity: 5/PK

• Brand: Cogent

Guard Column Holder Requirement

• A Cogent 10 mm ID Semi-Preparative Guard Column Holder is required for use with these guard cartridges.

• View the Cogent 10 mm ID Semi-Preparative Guard Column Holder (83000-SP-GH)

Important Notes

• Compatible with Cogent RP C8 Octyl semi-preparative HPLC columns

• Designed to intercept particulates and contaminants before they reach the analytical bed

• Recommended for routine purification and scale-up workflows

• Replace guard cartridges as needed based on sample cleanliness and application requirements