Catalog Number - 68008-PG2-3

Cogent RP C8 Octyl Wide Pore Guard Column Cartridges are packed with the same high-quality stationary phase used in Cogent RP C8 Wide Pore analytical columns. The 300 Å pore structure is specifically designed to improve accessibility for proteins, peptides, and other large molecules, while the fully double endcapped octyl (C8) bonded phase provides reliable chromatographic performance and excellent column protection in reversed-phase HPLC applications.

68008-PG2-3 contains five guard column cartridges packed with 10 µm RP C8 Octyl Wide Pore material featuring a 300 Å pore size in 4.0 mm ID x 10 mm length hardware. Designed for use with 3.0 mm, 4.0 mm, and 4.6 mm ID analytical RP C8 columns, these guard cartridges help intercept particulates, strongly retained contaminants, and sample matrix components before they reach the analytical column. The matching stationary phase chemistry helps maintain chromatographic selectivity while extending the useful life of analytical columns.

Used in analytical HPLC, biotechnology research, protein analysis, peptide separations, and method development laboratories, these guard cartridges help preserve column efficiency, improve reproducibility, and reduce replacement costs. The stainless steel cartridge construction incorporates stainless steel frits pressed into durable PEEK frit caps for reliable performance across a wide range of reversed-phase HPLC methods.

Key Benefits

• Packed with Cogent RP C8 Octyl Wide Pore stationary phase

• 300 Å pore size optimized for larger molecules

• Fully double endcapped chemistry

• Traditional octyl (C8) bonded phase

• Protects analytical HPLC columns from contaminants

• Helps maintain column efficiency and reproducibility

• Extends analytical column service life

• 10 µm particles for low operating backpressure

• Stainless steel cartridge construction

• Supplied as a convenient 5-pack

Typical Applications

• Protein analysis

• Peptide analysis

• Large molecule separations

• Biotechnology research

• Biopharmaceutical analysis

• Method development

• Quality control testing

• Analytical HPLC

• Sample cleanup and column protection

• Reversed-phase HPLC separations

Specifications

• Product Type: Guard Column Cartridges

• Stationary Phase: RP C8 Octyl Wide Pore

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double Endcapped

• Particle Size: 10 µm

• Pore Size: 300 Å

• Cartridge Dimensions: 4.0 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel with PEEK Frit Caps

• Quantity: 5/PK

• Compatible Column IDs: 3.0 mm, 4.0 mm, and 4.6 mm

• Brand: Cogent

Guard Column Holder Requirement

• A Cogent Guard Column Holder is required for use with these guard cartridges.

• View the Cogent Guard Column Holder (83000-GH)

Important Notes

• Compatible with Cogent RP C8 Octyl Wide Pore analytical HPLC columns

• Optimized for proteins, peptides, and other large molecules

• Designed to intercept particulates and contaminants before they reach the analytical column

• Recommended for routine analytical, biotechnology, and method development applications

• Replace guard cartridges as needed based on sample cleanliness and application requirements