Catalog Number - 68008-P21-PG1-3

Cogent RP C8 Octyl Wide Pore Guard Column Cartridges are packed with the same high-quality stationary phase used in Cogent RP C8 Wide Pore preparative columns. The 300 Å pore structure is specifically designed for proteins, peptides, and other large biomolecules, while the fully double endcapped octyl (C8) bonded phase provides reliable chromatographic performance and protection for preparative purification workflows.

68008-P21-PG1-3 is a preparative guard column cartridge packed with 10 µm RP C8 Octyl Wide Pore material featuring a 300 Å pore size in a 21.2 mm ID x 10 mm length stainless steel cartridge. Designed specifically for use with 21.2 mm ID preparative HPLC columns, this guard cartridge helps intercept particulates, strongly retained contaminants, and sample matrix components before they reach the preparative column. The 10 µm particle size provides low operating backpressure while maintaining compatibility with high-loading preparative purification applications.

Used in protein, peptide, and biomolecule purification workflows, this guard cartridge helps preserve preparative column efficiency, improve reproducibility, and reduce replacement costs. Stainless steel cartridge construction and frits provide durability for routine purification, process development, and scale-up chromatography applications. Regular guard cartridge replacement based on sample cleanliness and application requirements can significantly extend preparative column service life.

Key Benefits

• Packed with Cogent RP C8 Octyl Wide Pore stationary phase

• 300 Å pore size optimized for biomolecules

• Fully double endcapped chemistry

• Traditional octyl (C8) bonded phase

• Protects preparative HPLC columns from contaminants

• Helps maintain column efficiency and reproducibility

• Extends preparative column service life

• 10 µm particles for low operating backpressure

• Stainless steel cartridge construction

• Ideal for protein and peptide purification workflows

Typical Applications

• Preparative HPLC purification

• Protein purification

• Peptide purification

• Biomolecule isolation

• Fraction collection

• Process development

• Method scale-up

• Biotechnology research

• Biopharmaceutical purification

• Preparative column protection

Specifications

• Product Type: Preparative Guard Column Cartridge

• Stationary Phase: RP C8 Octyl Wide Pore

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double Endcapped

• Particle Size: 10 µm

• Pore Size: 300 Å

• Cartridge Dimensions: 21.2 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Quantity: 1 EA

• Brand: Cogent

Guard Column Holder Requirement

• A Cogent 21.2 mm ID Preparative Guard Column Holder is required for use with this guard cartridge.

• View the Cogent 21.2 mm ID Preparative Guard Column Holder (83000-P21-GH)

Important Notes

• Compatible with Cogent RP C8 Octyl Wide Pore preparative HPLC columns

• Optimized for proteins, peptides, and other large biomolecules

• Designed to intercept particulates and contaminants before they reach the preparative column

• Recommended for routine purification and scale-up workflows

• Replace as needed based on sample cleanliness and application requirements