Catalog Number - 68008-P21-PG1

Cogent RP C8 Octyl Guard Column Cartridges are packed with the same high-quality stationary phase used in Cogent RP C8 Octyl preparative columns, featuring traditional octyl (C8) silane bonding on high-purity silica with complete double endcapping. These guard cartridges are designed to intercept particulates, strongly retained contaminants, and sample matrix components before they reach the preparative column bed, helping maintain chromatographic performance and extend column life.

68008-P21-PG1 is a preparative guard column cartridge packed with 10 µm RP C8 Octyl material featuring a 100 Å pore size in a 21.2 mm ID x 10 mm length stainless steel cartridge. Designed specifically for use with 21.2 mm ID preparative HPLC columns, this guard cartridge provides an economical way to protect valuable preparative columns from contamination and premature fouling. The 10 µm particle size delivers low backpressure while maintaining compatibility with preparative purification workflows and high sample loading applications.

Used in purification and fraction collection workflows, this guard cartridge helps preserve preparative column efficiency, improve reproducibility, and reduce replacement costs. Stainless steel cartridge construction and frits provide the durability required for routine purification, process development, and scale-up chromatography. Regular replacement based on sample cleanliness and application requirements can significantly extend the service life of preparative columns.

Key Benefits

• Packed with Cogent RP C8 Octyl stationary phase

• Fully double endcapped chemistry

• Traditional octyl (C8) bonded phase

• Protects preparative HPLC columns from contaminants

• Helps maintain column efficiency and reproducibility

• Extends preparative column service life

• 10 µm particles for low operating backpressure

• Stainless steel cartridge construction

• Stainless steel frits

• Ideal for purification and scale-up workflows

Typical Applications

• Preparative HPLC purification

• Fraction collection

• Compound isolation

• Process development

• Method scale-up

• Pharmaceutical research

• Synthetic chemistry

• Natural product purification

• Production support purification

• Preparative column protection

Specifications

• Product Type: Preparative Guard Column Cartridge

• Stationary Phase: RP C8 Octyl

• Chromatography Mode: Reversed Phase

• Bonded Phase: Octyl (C8)

• Endcapping: Fully Double Endcapped

• Particle Size: 10 µm

• Pore Size: 100 Å

• Cartridge Dimensions: 21.2 mm ID x 10 mm

• Hardware Material: Stainless Steel

• Frit Material: Stainless Steel

• Quantity: 1 EA

• Brand: Cogent

Guard Column Holder Requirement

• A Cogent 21.2 mm ID Preparative Guard Column Holder is required for use with this guard cartridge.

• View the Cogent 21.2 mm ID Preparative Guard Column Holder (83000-P21-GH)

Important Notes

• Compatible with Cogent RP C8 Octyl preparative HPLC columns

• Designed to intercept particulates and contaminants before they reach the preparative column

• Recommended for routine purification and scale-up workflows

• Replace as needed based on sample cleanliness and application requirements