HPLC Column, RP C8 Octyl, 10um, 4.6mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent RP C8 Octyl is a reversed-phase HPLC stationary phase manufactured using high-purity silica with traditional octyl (C8) silane bonding and complete double endcapping. The moderate hydrophobicity of the C8 ligand provides an excellent balance between retention and elution strength, making it suitable for a broad range of hydrophobic and neutral compounds. This stationary phase is commonly selected as an alternative for USP methods that specify L7 column classifications and is frequently used when reduced retention compared to C18 phases is preferred.

68008-05P is an analytical HPLC column with dimensions of 4.6 mm ID x 50 mm length, packed with 10 µm RP C8 Octyl particles featuring a 100 Å pore size. The short 50 mm length is ideal for rapid method development, screening studies, and high-throughput analyses where fast run times are prioritized. The 10 µm particle size provides lower operating backpressure while supporting higher flow rates than smaller particle columns.

This column is well suited for analysis of hydrophobic and neutral compounds, including long-chain fatty acids and related analytes. The shorter column format also makes it an effective scouting column for preparative method development, allowing rapid evaluation of retention and selectivity prior to scale-up. Its combination of reduced retention, robust chemistry, and fast cycle times makes it valuable for routine analytical laboratories and method development groups.

Key Benefits

  • RP C8 Octyl stationary phase

  • Fully double endcapped chemistry

  • Traditional octyl (C8) bonded phase

  • Suitable alternative for USP L7 methods

  • Lower retention than C18 columns

  • 10 µm particles for lower operating backpressure

  • Short column for rapid analyses

  • Effective scouting column for preparative methods

  • High-purity silica support

  • Robust analytical performance

Typical Applications

  • USP L7 methods

  • Long-chain fatty acid analysis

  • Hydrophobic compound analysis

  • Neutral compound analysis

  • Method development

  • Method scouting

  • High-throughput testing

  • Pharmaceutical analysis

  • Quality control laboratories

  • Routine HPLC separations

Specifications

  • Product Type: Analytical HPLC Column

  • Stationary Phase: RP C8 Octyl

  • Chromatography Mode: Reversed Phase

  • USP Classification: L7

  • Bonded Phase: Octyl (C8)

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.6 mm ID x 50 mm

  • Length: 50 mm

  • Typical Flow Rate: 1.0–2.0 mL/min

  • Brand: Cogent

Important Notes

  • Suitable as an alternative for USP L7 methods

  • Provides less retention than C18 stationary phases

  • Commonly used for long-chain fatty acid separations

  • Ideal for fast analytical methods and method scouting

  • Can be used to evaluate selectivity prior to preparative scale-up


 

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