HPLC Column, IEX SCX, 10um, 4.6mm ID x 100mm Length, 100A. Cogent Brand. 1 EA.
Additional Information:
Cogent IEX SCX is a strong cation exchange (SCX) HPLC stationary phase manufactured using high-purity silica and sulfonic acid functional groups that maintain a permanent negative charge across a wide pH range. This strong cation exchange mechanism provides reliable retention and separation of positively charged analytes, making the column suitable for ion exchange chromatography methods involving basic compounds, amines, peptides, pharmaceuticals, and other cationic species. The stationary phase is an excellent alternative for USP L9 methods and applications requiring robust cation exchange selectivity.
67086-10P is a 100 mm x 4.6 mm ID analytical column packed with 10 µm SCX particles with a 100 Å pore size. The 100 mm length provides an excellent balance between chromatographic resolution and analysis time, while the larger 10 µm particle size delivers low backpressure and supports higher flow rates compared to smaller particle packings. Typical operating flow rates are approximately 1.0–3.0 mL/min, making this column well suited for conventional HPLC systems and routine ion exchange methods.
This USP L9 column is particularly useful for the separation and purification of positively charged compounds, including basic pharmaceuticals, amines, peptides, alkaloids, and other ionic species. The combination of strong cation exchange functionality, high capacity, and low backpressure makes it ideal for routine analytical testing, method development, quality control laboratories, and purification workflows.
Key Benefits
Strong cation exchange (SCX) stationary phase
Sulfonic acid functional groups
Permanent negative surface charge
Suitable alternative for USP L9 methods
10 µm particles for lower backpressure
Supports higher flow rates
Balanced resolution and analysis time
High-purity silica support
Typical Applications
USP L9 methods
Ion exchange chromatography
Basic compound analysis
Pharmaceutical analysis
Amine separations
Peptide analysis
Method development
Quality control testing
Specifications
Product Type: HPLC Column
Stationary Phase: IEX SCX
USP Classification: L9
Chromatography Mode: Strong Cation Exchange
Functional Group: Sulfonic Acid
Particle Size: 10 µm
Pore Size: 100 Å
Column Dimensions: 4.6 mm ID x 100 mm
Length: 100 mm
Recommended Flow Rate: 1.0–3.0 mL/min
Brand: Cogent
Important Notes
Designed for ion exchange chromatography
Retains positively charged analytes
Sulfonic acid groups remain charged across a broad pH range
100 mm length balances resolution and run time
Lower backpressure compared to smaller particle columns
Supports higher flow rates for routine methods
Excellent alternative for many USP L9 methods