Catalog Number - 67085-15P

Cogent IEX SAX is a strong anion exchange (SAX) HPLC stationary phase manufactured using high-purity silica and quaternary amine functional groups that maintain a permanent positive charge across a wide pH range. This strong anion exchange mechanism provides reliable retention and separation of negatively charged analytes, making the column suitable for ion exchange chromatography methods involving inorganic anions, organic acids, biomolecules, and other ionic compounds. The stationary phase is an excellent alternative for USP L9 methods and applications requiring robust anion exchange selectivity.

67085-15P is a 150 mm x 4.6 mm ID analytical column packed with 10 µm SAX particles with a 100 Å pore size. The 150 mm length provides increased resolving power for more demanding ion exchange separations while maintaining the low backpressure advantages associated with 10 µm particles. This configuration is well suited for complex samples requiring greater retention and improved separation of closely related anionic species. Typical operating flow rates are approximately 1.0–3.0 mL/min on conventional HPLC systems.

This USP L9 column is particularly useful for the separation and purification of negatively charged compounds, including organic acids, inorganic anions, nucleotides, and other ionic species. The combination of strong anion exchange functionality, high capacity, and low backpressure makes it ideal for routine analytical testing, method development, purification workflows, and quality control laboratories requiring enhanced chromatographic resolution.

Key Benefits

• Strong anion exchange (SAX) stationary phase

• Quaternary amine functional groups

• Permanent positive surface charge

• Suitable alternative for USP L9 methods

• 10 µm particles for lower backpressure

• Supports higher flow rates

• Increased resolution from 150 mm column length

• High-purity silica support

Typical Applications

• USP L9 methods

• Ion exchange chromatography

• Organic acid analysis

• Inorganic anion separations

• Biomolecule analysis

• Method development

• Purification studies

• Quality control testing

Specifications

• Product Type: HPLC Column

• Stationary Phase: IEX SAX

• USP Classification: L9

• Chromatography Mode: Strong Anion Exchange

• Functional Group: Quaternary Amine

• Particle Size: 10 µm

• Pore Size: 100 Å

• Column Dimensions: 4.6 mm ID x 150 mm

• Length: 150 mm

• Recommended Flow Rate: 1.0–3.0 mL/min

• Brand: Cogent

Important Notes

• Designed for ion exchange chromatography

• Retains negatively charged analytes

• Quaternary amine groups remain charged across a broad pH range

• Increased resolving power for complex separations

• Lower backpressure compared to smaller particle columns

• Supports higher flow rates for routine methods

• Excellent alternative for many USP L9 methods

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