Catalog Number - 64424-05P

Nova Similars Phenyl™ is a traditional reversed-phase HPLC stationary phase manufactured on high-purity Type-B spherical silica with a fully endcapped phenyl bonded phase. The stationary phase consists of a four-carbon linker terminating in a phenyl functional group, providing unique selectivity based on both hydrophobic and π-π interactions. Designed as a cost-effective alternative to Waters™ Nova-Pak® Phenyl columns, it offers comparable chromatographic behavior for USP L11 methods while maintaining the reliability and reproducibility required for routine analytical applications.

64424-05P is a 50 mm x 4.6 mm ID analytical column packed with 4 µm Nova Similars Phenyl particles. The short 50 mm length is optimized for rapid analyses, fast equilibration, and reduced solvent consumption. The 4 µm particle size provides improved efficiency and sharper peaks than comparable 5 µm columns while maintaining moderate operating pressure on conventional HPLC systems. Typical operating flow rates are approximately 1.0–2.0 mL/min.

This USP L11 column is particularly useful for aromatic compounds where phenyl selectivity can provide different retention characteristics than traditional C18 phases. Common applications include pharmaceuticals, aromatic hydrocarbons, environmental compounds, and methods requiring enhanced aromatic selectivity through π-π interactions.

Key Benefits

• Type-B spherical silica stationary phase

• Suitable alternative for USP L11 methods

• Comparable selectivity to Waters™ Nova-Pak® Phenyl columns

• Fully endcapped phenyl bonded phase

• Enhanced aromatic compound selectivity

• Fast analysis with 50 mm column length

• Higher efficiency than comparable 5 µm columns

• Unique π-π interaction mechanism

Typical Applications

• USP L11 methods

• Reversed-phase HPLC

• Pharmaceutical analysis

• Aromatic compound separations

• Environmental testing

• Method development

• Quality control testing

• Method transfer and validation

Specifications

• Product Type: HPLC Column

• Stationary Phase: Nova Similars Phenyl

• USP Classification: L11

• Particle Size: 4 µm

• Particle Type: Type-B Spherical Silica

• Bonded Phase: Phenyl

• Endcapped: Fully

• Column Dimensions: 4.6 mm ID x 50 mm

• Length: 50 mm

• Recommended Flow Rate: 1.0–2.0 mL/min

• Brand: Cogent

Important Notes

• Designed for reversed-phase chromatography

• Phenyl selectivity provides different retention than C18 phases

• Enhanced interactions with aromatic compounds

• Short column length provides rapid analyses

• Higher efficiency than comparable 5 µm columns

• Moderate operating pressure on conventional HPLC systems

• Excellent alternative for many USP L11 methods

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