Catalog Number - 58846-09

58846-09 ARE‑Applied Research Mobile Phase Inlet Filter is a high‑capacity, biocompatible solvent filtration device engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing maximum solvent recovery, ultra‑low flow restriction, and consistent protection of system components.

This filter features a “Last Drop” flat‑profile design, enabling nearly complete withdrawal of solvent from reservoir bottles—making it especially valuable for high‑flow systems, large‑volume solvent workflows, and extended analytical runs.

Constructed with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, this filter offers exceptional chemical compatibility, minimal extractables, and long service life, particularly in applications where flow rate and throughput are prioritized.

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Designed to sit at the lowest point in the reservoir bottle

• Draws solvent to near‑empty conditions

• Reduces waste and prevents pump run‑dry events

✅ Ideal for bulk solvent handling, high‑throughput labs, and long runs

✅ Improves operational efficiency and cost control

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Lowest flow restriction in the series

  • Longest service life between replacements

✅ Ideal for high‑flow systems and pre‑filtered mobile phases

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables quick contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Ensures:

  • Chemical inertness

  • Minimal extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/8" Connector with ETFE Ferrule – High‑Flow Integration

• Integrated 1/8" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Ideal for higher flow rate systems and larger tubing configurations

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest restriction → maximum throughput

• Reduced clogging risk

• Improved flow stability under demanding conditions

• Extended filter lifespan

✅ Ideal for high‑efficiency, high‑volume analytical environments

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline solvent filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and delivery

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• Routine analytical laboratory operations

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with included ferrule

• Inspect filter element periodically for buildup

• Replace when flow performance declines