Catalog Number - 58846-08

58846-08 ARE‑Applied Research Mobile Phase Inlet Filter is a biocompatible, high‑capacity solvent filtration device designed for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, offering maximum solvent recovery, ultra‑low flow restriction, and dependable protection of system components.

This filter incorporates a “Last Drop” flat‑profile design, allowing nearly complete withdrawal of solvent from the reservoir bottle—especially advantageous for high‑throughput labs, long run times, and bulk solvent handling.

Manufactured with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, this inlet filter delivers excellent chemical compatibility, minimal extractables, and exceptional flow performance, making it ideal for applications where flow rate and capacity are prioritized.

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Designed to rest at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and reduces risk of pump run‑dry

✅ Ideal for bulk solvent use, long sequences, and high‑volume workflows

✅ Improves operational efficiency and cost control

10 µm PTFE Element – Ultra‑High Flow / Maximum Capacity

• Removes particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injector components

  • Columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal flow restriction

  • Longest service life among pore size options

✅ Ideal for high‑flow systems and pre‑filtered solvent applications

Visual Inspection Advantage – White Filter Element

• White PTFE surface allows easy visibility of trapped particles

• Enables quick inspection of contamination buildup

• Supports timely replacement for optimal flow performance

✅ Helps maintain consistent solvent delivery and system reliability

PEEK / PTFE Flow Path – High Purity Performance

• Wetted components made from:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Low extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

1/16" Connector with ETFE Ferrule – Secure Integration

• Integrated 1/16" tubing connector

• Includes ETFE ferrule for non‑flanged tubing

• Provides secure, leak‑free connection

• No additional fittings required

✅ Enables fast, reliable low‑pressure system setup

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore size filters:

• Lowest flow restriction available in this series

• Reduced clogging risk

• Superior flow stability in demanding applications

• Extended operating life between replacements

✅ Ideal for high‑efficiency, high‑throughput laboratory environments

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing systems (1/16")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent handling and staging

• LC‑MS solvent protection

• Pre‑filtered solvent systems

• Routine analytical laboratory workflows

• Long‑duration and unattended chromatographic runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure proper tubing installation with included ferrule

• Inspect for particulate buildup periodically

• Replace filter when flow performance declines