Catalog Number - 58846-01

58846-01 ARE‑Applied Research Mobile Phase Inlet Filter is a high‑capacity, biocompatible solvent filtration device engineered for HPLC, UHPLC, and LC‑MS mobile phase delivery systems, providing maximum solvent recovery, ultra‑low flow restriction, and dependable protection of critical system components.

This filter features a “Last Drop” flat bottom‑draw design, allowing nearly complete withdrawal of solvent from reservoir bottles—an essential advantage for high‑throughput workflows, long analytical runs, and bulk solvent usage where minimizing waste and avoiding interruptions is critical.

Constructed with a 10 µm PTFE filter element and an inert PEEK / PTFE wetted flow path, this inlet filter delivers excellent chemical compatibility, minimal extractables, and extended service life, especially in applications prioritizing high flow efficiency and durability.

“Last Drop” Design – Maximum Solvent Utilization

• Wide 22 mm flat bottom‑draw geometry

• Sits at the lowest point in the bottle

• Draws solvent to near‑empty conditions

• Minimizes waste and prevents pump starvation

✅ Ideal for high‑volume solvent use and extended analytical sequences

✅ Improves efficiency and solvent cost control

10 µm PTFE Element – Ultra‑High Flow Capacity

• Filters particles ≥ 10 µm

• Protects:

  • Pump seals and check valves

  • Injection systems

  • HPLC columns and detectors

• Larger pore size provides:

  • Maximum flow capacity

  • Minimal restriction / lowest backpressure

  • Longest service life in the filter family

✅ Ideal for pre‑filtered solvents and high‑flow chromatography systems

Visual Inspection Advantage – White Filter Element

• White PTFE surface enhances visibility of trapped particles

• Enables rapid contamination assessment

• Helps determine optimal replacement timing

✅ Supports proactive maintenance and consistent system performance

PEEK / PTFE Flow Path – High Purity Performance

• Wetted materials:

  • PEEK (polyether ether ketone)

  • PTFE (inert fluoropolymer)

• Provides:

  • Chemical inertness

  • Low extractables and leachables

  • Broad solvent compatibility

✅ Suitable for LC‑MS, analytical, and biocompatible workflows

Tripod Connector – Universal, Tool‑Free Integration

• All‑PEEK tripod tubing connector

• Accepts:

  • 1/16" OD tubing

  • 1/8" OD tubing

• No ferrules or nuts required

• Simple push‑fit tubing installation and removal

✅ Enables fast setup and flexible system configuration across multiple tubing sizes

Performance Advantages – High‑Flow Chromatography Systems

Compared to smaller pore filters:

• Lowest flow restriction for maximum throughput

• Reduced clogging risk

• Improved solvent delivery stability at high flow rates

• Extended intervals between maintenance

✅ Aligns with best practices for high‑efficiency, high‑throughput chromatography systems

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase systems

• LC‑MS solvent delivery setups

• Low‑pressure tubing configurations (1/16" and 1/8")

• Standard mobile phase reservoir bottles

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• High‑flow HPLC mobile phase filtration

• Bulk solvent preparation and handling

• LC‑MS solvent protection

• Pre‑filtered solvent workflows

• High‑throughput analytical laboratories

• Long‑duration and unattended runs

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure systems only

• Ensure tubing is properly seated for leak‑free performance

• Inspect filter element periodically for buildup

• Replace when flow performance declines