Catalog Number - 58835-01

58835-01 ARE‑Applied Research Mobile Phase Inlet Filter is a high‑performance solvent filtration device designed to protect HPLC, UHPLC, and LC‑MS systems while maximizing mobile phase utilization.

This advanced “Last Drop” design ensures that nearly all solvent in the bottle can be used efficiently, reducing waste and maintaining uninterrupted system operation—especially valuable in long runs and high‑throughput environments.

Constructed with a 2 µm stainless steel filter element and an all‑PEEK/PTFE fluid path, this filter delivers exceptional chemical resistance, high flow capacity, and minimal contamination risk.

“Last Drop” Design – Maximum Solvent Utilization

• Flat, wide 22 mm filter profile

• Sits low in the bottle to access nearly all liquid

• Creates a slight “vacuum effect” to draw remaining solvent

• Minimizes waste and prevents system run‑dry events

✅ Ideal for overnight runs, long sequences, and high‑value solvents

✅ Improves lab efficiency and solvent cost management

2 µm Stainless Steel Element – System Protection

• Filters particles ≥ 2 µm

• Prevents debris from entering:

  • HPLC pumps

  • Columns

  • Valves and detectors

• High surface area supports:

  • High flow rates

  • Low restriction

  • Extended service life

✅ Critical for protecting instrumentation and maintaining data integrity

PEEK / PTFE Flow Path – Chemical Purity

• All wetted components made from:

  • PEEK (Polyether Ether Ketone)

  • PTFE (Teflon®)

• Ensures:

  • Chemical inertness

  • Low extractables

  • Compatibility with aqueous and organic solvents

✅ Suitable for high‑purity analytical and LC‑MS applications

Tripod Connector – Tool‑Free Tubing Integration

• Unique tripod‑style PEEK connector

• Accepts:

  • 1/16" OD tubing

  • 1/8" OD tubing

• Internal ID ~0.8 mm

• No ferrules or nuts required

• Simple push‑fit installation

✅ Enables fast setup and reliable low‑pressure connections

Performance Advantages (Industry Context)

Compared to conventional inlet filters, “Last Drop” style filters offer:

• Greater solvent recovery efficiency

• Reduced risk of air introduction into pumps

• Improved flow stability near empty conditions

• Lower operator intervention during runs

Modern HPLC best practices emphasize high‑surface‑area, low‑restriction inlet filters to:

• Maintain consistent flow

• Protect check valves and seals

• Extend column lifetime

✅ These filters align with current chromatography system protection standards

System Compatibility & Use

Designed for use with:

• HPLC / UHPLC mobile phase bottles

• LC‑MS solvent delivery systems

• Low pressure tubing configurations

• Standard mobile phase reservoirs

✅ Installs directly into mobile phase bottles for inline filtration

Typical Applications

• HPLC mobile phase filtration

• LC‑MS solvent protection

• High‑throughput analytical labs

• Pharmaceutical and QA/QC workflows

• Long‑run chromatography sequences

• Integrated into original equipment manufacturer (OEM) product designs

Important Usage Notes

• Designed for low‑pressure solvent delivery systems only

• Ensure proper tubing fit for leak‑free operation

• Periodically inspect and clean filter as needed

• Replace when flow restriction increases