Syringe Filters, 25mm, Nylon, 0.22um Pore Size. Purple Polypropylene, AQ Brand. 50/PK.
Additional Info:
The 58022-N25-A AQ™ Syringe Filters are pharmaceutical-grade, high-performance membrane filters engineered for HPLC sample preparation, sterile filtration, and dissolution testing in regulated laboratory environments. Featuring a 0.22 µm Nylon‑66 membrane, these filters deliver exceptional consistency, ultra-low adsorption, and extractable-free performance, ensuring maximum sample purity and reproducible analytical results.
The 0.22 µm pore size is optimized for sterile filtration and fine particulate removal, making these filters ideal for critical analytical workflows where sample clarity and system protection are essential.
✅ Critical Compliance Advantage (No Flush Required)
These filters are validated and certified to meet stringent regulatory requirements, including:
US FDA CFR Title 21, Part 210.3(b)(6) for minimum fiber release
USP <788> for particulate matter in injectables
USP requirements for “Sterile Water for Injection”
Because of this validated performance:
✅ No initial flushing is required
✅ No need to discard the first 200 µL of filtrate
✅ Preserves valuable sample and saves analyst time
✅ Reduces risk of failed methods and costly investigations
👉 This provides a critical operational and compliance advantage for QC/QA laboratories, where reproducibility, documentation, and efficiency are essential.
Performance & Design
The advanced 16-channel outlet design minimizes back pressure, enabling smooth filtration with reduced hand force, improving ergonomics and throughput in high-volume workflows.
Nylon‑66 membrane chemistry ensures broad compatibility with aqueous and organic HPLC solvents, while maintaining ultra-low adsorption—even for charged analytes, supporting accurate quantitation.
The 25 mm diameter supports higher sample throughput, and the purple color coding allows quick identification of 0.22 µm nylon filters.
Each pack is supplied with a Certificate of Analysis, ensuring traceability and compliance in regulated environments.
Key Features
0.22 µm Nylon‑66 Membrane (Pharma Grade)
Ideal for sterile filtration and fine particulate removal
Ensures maximum sample clarity
✅ No Initial Flush Required (Validated)
Extractable-free from first filtrate
Eliminates sample waste and variability
Ultra-Low Adsorption
Suitable for charged and sensitive analytes
Maximizes analyte recovery
Advanced 16-Channel Outlet Design
Reduces back pressure
Requires less hand force
Regulatory Compliance
Meets FDA CFR Title 21 requirements
Complies with USP <788>
Suitable for Sterile Water for Injection
Broad Solvent Compatibility
Compatible with aqueous and organic solvents
Ideal for mixed HPLC mobile phases
25 mm Diameter for High Throughput
Handles larger sample volumes
Improves lab productivity
Autoclavable & EO Sterilizable
121°C for 30 minutes or Ethylene Oxide
Color-Coded (Purple)
Identifies 0.22 µm nylon filters
Typical Applications
HPLC & UHPLC Sample Preparation – fine particulate removal prior to injection
Sterile Filtration – bacterial and particulate removal
Dissolution Testing – pharmaceutical QC and release workflows
Regulated Laboratory Methods – validated, compliant processes
Pharmaceutical Analysis – injectables and formulations
Aqueous & Organic Filtration – mixed solvent systems
Specifications
Filter Type: Syringe Filter (Pharma Grade)
Membrane Material: Nylon‑66
Pore Size: 0.22 µm
Diameter: 25 mm
Housing Material: Polypropylene (PP)
Color Code: Purple (0.22 µm Nylon)
Connection Type: Luer Lock / Slip
Chemical Compatibility: Aqueous and organic solvents
Extractables: None detectable (no flush required)
Sterilization: Autoclave or EO
Compliance: FDA CFR 21, USP <788>
Certification: Certificate of Analysis included
Sterility: Non-sterile
Pack Size: 50/PK
Brand: AQ™
Resources & Ordering Options
Order Nylon‑66 syringe filters, 0.22 µm, 25 mm – 1000/case quantity
Purchase Nylon‑66 syringe filters, 0.22 µm, 25 mm – 100/pack quantity