The Cogent TYPE-C Silica™ columns have been observed to last 20-50% longer than those based on ordinary silica under normal conditions. What this means is following the specifications of the columns in terms of temperature, pH, and so on. In addition, please be sure to follow proper storage protocols to make sure the material is not damaged due to bonded phase loss, silica dissolution, buffer precipitation, stainless steel pitting, or drying out.