Excellent Peak Shape and Resolution
This Method is easy to prepare, use and reproduce. Good Peak shape and Resolution is observed for Simvastatin from its hydrolysis products and tablet Excipients.
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Column: Cogent Bidentate C18™, 4μm, 100Å
Catalog No.: 40018-75P
Dimensions: 4.6 x 75mm
Mobile Phase: 52% DI Water / 60% Acetonitrile / 10mM Sodium Phosphate
Flow rate: 1.5mL / minute
Detection: UV @ 238nm
Injection vol.: 10μL
Notes: Simvastatin is marketed under the trade names Zocor, Simvastatin, Simlup, Simcard and others. It is a hypolipidemic drug belonging to the class of pharmaceuticals called “statins”. It is used to control hypercholesterolemia (elevated cholesterol levels) and to prevent cardiovascular disease. Simvastatin is a synthetic derivate of a fermentation product of Aspergillus Terreus.
No 83 Simvastatin Analyzed with HPLC pdf 0.1 Mb Download File