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Cogent Silica-C

1 Are the Cogent Silica-C columns stable?

Yes, we have done extensive testing in our labs and in real world use around the world and have proven that the Cogent Silica-C™ columns are stable even in the presence of water. However, these columns…

2 Can I expect a more predictable retention time with Silica-C columns?

Yes, if you develop a method that is optimized with the Cogent Silica-C™ columns compared with an ordinary silica column, the retention times are generally much more reproducible. The reason is most…

3 Can I use Silica-C™ columns in a Normal Phase Gradient method?

Yes, although this is not easy with ordinary silica columns due to solvent de-mixing & water uptake, the Cogent Silica-C™ column is not limited by this and is easy to use. © Copyright MicroSolv…

4 Can I use triethylamine (TEA) with a Silica-C column?

The triethylamine (TEA) additive is compatible with Silica-C™ columns in the sample diluent or mobile phase as long as the concentration is not excessive and the mobile phase pH is kept within the specifications…

5 Does the Silica-C™ column have any carbon in it?

No, the Cogent Silica-C™ column is totally inorganic and is made completely of silicon, hydrogen and oxygen. Any apparent retention of non polar compounds you may observe is most likely aqueous normal…

6 How do I condition new Cogent TYPE-C™ Columns for use?

For all new Cogent TYPE-C™ HPLC columns with the exception of new Diamond Hydride™ columns, all one needs to do is run 7-10 column bed volumes of your mobile phase through the column at your normal…

7 Is TYPE-C Silica™ high purity and low metal content silica like Type silica?

Yes, it is and it has all the advantages of ordinary, market leading high purity, type-B silica supports for HPLC. © Copyright MicroSolv Technology Corporation, all rights reserved.

8 What is the biggest difference between ordinary HPLC silica columns and Silica-C™?

The biggest difference is the surface chemistry and how it will benefit you. The dominance of silicon hydride (Si-H) groups instead of the “silanol group” (Si-OH) common to all irregular or spherical…

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