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Effect of Diluent on Analyte Adsorption to RSA Glass Vials

Reference Number: AA-02057 Created: 01/08/2014 12:23 PM Last Updated: 07/27/2017 02:21 PM

It is well known that silanol groups present on the surface of Type I autosampler glass vials contribute to quantitative loss in the case of basic analytes. This is believed to occur primarily by electrostatic interaction and possibly by hydrogen bonding to some degree. In order to investigate the nature of this interaction in more detail, we conducted a series of experiments using different sample diluents.

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 RSA Glass Vials Product Page

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