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What is the structure of the Cogent Phenyl Hydride bonded ligand? What is a "direct silicon-carbon bond"?

Reference Number: AA-01068 Created: 12/04/2012 03:32 PM Last Updated: 07/23/2016 12:16 PM

The Cogent Phenyl Hydride phase is a 4 carbon chain with a phenyl group at the end attached directly to the silica hydride surface with a single, direct silicon-carbon bond.

With bonds in traditional silica B based materials, the organo-silane starting material is Si-O-Si-C4-Phenyl and this reagent is reacted with the silica to form the final stationary phase which includes a Si-O-Si-C4-Phenyl ligand. This is in contrast with the TYPE-C phases in that the Si-C bond is formed directly as part of the reaction resulting in Si-C4-Phenyl without the oxygen in the link which is very susceptible to hydrolysis.

More information on Phenyl Hydride HPLC Columns 

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